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" Calma (Remix)" – Pedro Capó and Farruko.Music Best Song: Can't Get Enough of This Song Anuel AA, Bad Bunny and Cardi B had the most wins of the night, taking home three awards each, followed by Daddy Yankee, Karol G and Maluma, who won two each. Maluma had the most nominations with eight, followed by Bad Bunny and Daddy Yankee behind with seven each, and Becky G, Anuel AA, J Balvin and Karol G all with six. The official nominees were revealed on May 21, 2019. Emilio Osorio and Joaquín Bondoni – introduced Reykon and Maluma.

Pabllo Vittar, Emilia and Chesca – introduced Pedro Capó, Farruko and Lali.Amara La Negra and Gerardo Ortiz – introduced Romeo Santos, El Chaval de la Bachata and Frank Reyes.Maite Perroni – presented Regional Roots 2.0 award.Cierra Ramirez – introduced Cazzu, Eladio Carrion, Amenazzy and Lyanno.Mané de la Parra and Michelle Renaud – introduced Sebastián Yatra and Tini.Karol Sevilla – introduced Silvestre Dangond and Cedric Gervais.Pepe Aguilar – introduced Christian Nodal, Ángela Aguilar and Pipe Bueno.Sebastián Yatra – presented Best LOL Award.Renata Notni and Sebastián Rulli – introduced Dalex, Sech, Cazzu, Feid and Rafa Pabön.Isabela Moner, Eugenio Derbez, Eva Longoria and Jeff Wahlberg – presented Singer + Songwriter + Composer award.
